Jean Chen Shih

  • USC University Professor
  • Holder of the Boyd P. and Elsie D. Welin Professorship in Molecular Pharmacology and Toxicology
  • Professor of cell and neurobiology
  • Professor, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences
  • Member, USC Program in Neural, Informational and Behavioral Sciences
Office: (323) 442-1441

Expertise Summary

Expert in cancer genetics and pathologies, tumor progression, clocks, and methods of growth


  • stress and its effects on brain chemistry
  • molecular pharmacology and toxicology
  • biochemistry and neurochemistry
  • biochemical processes and aging
  • molecular and biochemical bases of depression, memory, sleep, aggression, appetite and sexual behavior
  • neurobiology
  • enzyme regulation
  • gene expression
  • molecular biology
  • pharmacogenetics - study of how genetic diversity afffects the efficacy and side effects of drugs
  • serotonin receptors
  • monoamine oxidase (MAO)
  • genes and behavior
  • gene knock-out mice


  • Chinese

Additional Information

    • President of Society for Chinese American Neuroscientists (1994-96)


    • Co-founder of Cocensys, a biotechnology company to develop therapeutic


    • agents for disorders of the central nervous system


    • Shih and her collaborators are the first to have modeled the three-dimensional


    • structure of the brain enzyme monoamine oxidase (MAO)


    Two-time recipient of NIH Merit Award