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Aging - Alzheimer's Disease
News Listing
A multidisciplinary team has developed a selective compound that inhibits an enzyme tied to inflammation in people at genetic risk for Alzheimer’s — while preserving normal brain function and crossing the blood-brain barrier.
USC Life Trustee Daniel J. Epstein; his wife, Phyllis; and their family have been the philanthropic leaders behind the university’s world-leading efforts to make Alzheimer’s a memory.
USC, Cedars-Sinai and UCLA receive a $6.5 million grant from the National Institute on Aging — part of the National Institutes of Health — to create the Claude D. Pepper Older Americans Independence Center.
USC Dornsife psychologist Duke Han is co-leading the nationwide effort, which is funded by the National Institute on Aging.
The technique reveals how tiny blood vessels in the brain pulse with each heartbeat — changes that may hold clues to aging and diseases such as Alzheimer’s.
By focusing on a trigger of brain inflammation, scientists are in pursuit of a new drug therapy and now understand why some with a key risk factor for the disease develop dementia.
“Biological stochasticity” — random events at the molecular and cellular level — might be one of the biggest, most overlooked drivers of differences in how we age, a USC gerontology expert says.
Research indicates how iron-related oxidative damage and cell death may hasten the development of Alzheimer’s disease in people with Down syndrome.
Research uncovers a mechanism that protects the genome by avoiding catastrophic errors when repairing breaks in tightly packed DNA, a finding with implications for cancer and aging.